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Current Affairs

Antiviral drug MK-4482

Date: 19 April 2021 Tags: Miscellaneous

Issue

Experimental anti-viral drug MK-4482 has showed a strong ability to decrease viral levels and lungs damage against SARS-CoV-2 infection.

 

Background

The study was conducted in infected hamsters by US National Institutes of Health. It shows a lot of promise to treat serious infection.

 

Details

  • MK-4482 drug was delivered orally to humans in trials in comparison to remdesivir, which is given intravenously.

  • The use of the drug MK-4482 was found effective in hamsters when they were given the drug 12 hours before or 12 hours after getting infected by SARS-CoV-2 virus.

  • The results suggest that the drug can be used to treat serious cases of the infection as a standalone or in combination with other drugs.

 

The study

  • The animals used in the treatment groups had 100 times less infections in their lungs than the control group of animals.

  • Previous forms of study have also indicated that MK-4482 was indeed effective at stopping the viruses from replicating.