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Tags Current Affairs

Anti-body cocktail

Date: 10 May 2021 Tags: Miscellaneous

Issue

India’s CDSCO has approved an investigational anti-body cocktail produced by Swiss company Rosche for Covid-19 treatment.

 

Background

The cocktail of anti-body was used as a treatment for former US President Donald Trump when he was infected with the virus.

 

Details

  • The antibody cocktail is made up of two antibodies casirivimab and imdevimab and is used in treatment of mild and moderate cases of Covid-19 in high-risk patients.

  • The two antibodies are monoclonal antibodies and are artificial proteins made in laboratories.

  • They have the ability to fight pathogens such as virus by mimicking body’s natural immune system. They are directed at the spike protein of the SARS CoV-2 virus.

  • The cocktail contains antibodies that attach to two different parts of the spike protein and thus remains more effective in tackling mutated versions of the virus.

 

Usage of cocktail

  • The cocktail is used for treatment of high risk adults and paediatric patients who have moderate and mild cases of the infection.

  • The drug has to be administered through the intravenous infusion or subcutaneous route and stored at temperatures of 2°C to 8°C.

  • High risk patients include those individuals having cardiovascular disease, kidney disease, diabetes, chronic lung etc and above the age of 60 years.

 

Effectiveness

  • The trials conducted on patients all over the world showed that the drug reduced the risk of hospitalisation or death by 70%.

  • The cocktail drug has also shown ability to reduce the symptom duration by four days. It has also been successful in decreasing severity.

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