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IIT Researchers identify new method to detect breast, ovarian cancer

Date: 20 April 2019 Tags: Biotechnology

Researchers from Indian Institute of Technology, Roorkee have developed new salvia based non-invasive method to detect breast and ovarian cancer. This method uses certain proteins present in saliva which act as potential biomarker indicative of breast and ovarian cancer metastasis.

New Method

  • It is based on conception that certain proteins present in saliva that could act as salivary biomarkers in diagnosis of breast and ovarian cancers.
  • Researchers had identified total of 646 proteins, of which 409 proteins were confidently identified across all four groups.
  • In addition to 409 identified proteins, 352 proteins were common in all blood groups, while 57 were either present or absent exclusively in one group or common in any two/three blood groups.
  • It can be also used in patients who have undergone three cycles of chemotherapy, salivary proteins can also act as indicator of patients’ response to chemotherapy.


Breast and ovarian cancers are two of the worst forms of cancer, which are responsible for approximately one third of all cancers that occur in women and one fifth of all cancer related deaths worldwide. Their early detection has been difficult using traditional methods such as mammography, blood flow patterns by colour flow Doppler imaging and trans-vaginal ultrasound examination. This was mainly due to high diagnostic costs and radiation exposure because of heterogeneous and symptomatic nature of breast and ovarian cancers.

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