- India defeated South Africa by 113 runs to win the first Test match of the Test Series at Centurion.
- India became the first Asian team to win a Test match at Centurion and now take a 1-0 lead in the three match series.
- The year 2021 is the second time India has won four Tests outside Asia in a calendar year (Brisbane, Lord's, Oval, Centurion). The previous instance was in 2018 (Johannesburg, Nottingham, Adelaide, Melbourne).