Scientists at the University of Washington School of Medicine have devised artificial proteins that can regulate gene expression inside human T-cells. These proteins can function as molecular logic gates, tools are used to program the behavior of more complex systems.
With the right gates operating inside living cells, inputs such as the presence of two different molecules, or one and not the other, can cause a cell to produce a specific output, such as activating or suppressing a gene.
Genetically altered T cells can fight for only so long before they stop working. There may be a way around this. With protein logic gates that respond to exhaustion signals, the team from UW Medicine hopes to prolong the activity of CAR T cells.
Keir Starmer, the former shadow Brexit Secretary, emerged as the winner of a three-way race to replace Jeremy Corbyn as the Leader of the U.K.’s Opposition Labour party.
The 57-year-old was elected after he defeated Rebecca Long-Bailey and Indian-origin MP Lisa Nandy, who were a distant second and third respectively in a postal ballot of party members, trade unionists and registered supporters.
The lawyer-turned-politician has previously led the U.K.’s Crown Prosecution Service (CPS) and served in Corbyn’s top team for more than three years and was the face of the party’s Brexit policy.
Actor Logan Williams, who played young Barry Allen in The Flash, has died at the age of 16.
Williams last appeared on The Flash in the season 2 premiere, which aired in 2015. He also starred as Miles Montgomery on “When Calls the Heart” from 2014 to 2016 and appeared in “Supernatural”, “The Whispers”, and the TV movie “The Color of Rain”.
The Atacama Large Millimeter/submillimeter Array (ALMA) in Chile, the world's largest multi-dish radio telescope, has temporarily closed operations due to the spread of COVID-19 in the country.
Located in the Atacama Desert of northern Chile, ALMA comprises 66 high-precision antennas, spread over distances of up to 16 kilometres.This global collaboration is the largest ground-based astronomical project in existence.
This shutdown will enable ALMA staff to reduce social contact, better protect them and their families, and help reduce the spread of the virus.