Issue
A novel computer algorithm has shown its ability to produce influenza vaccine for swine flu and also offers a path toward a pan-coronavirus vaccine as well.
Background
The algorithm is known as Epigraph and has already been used to predict therapeutic HIV vaccine candidates.
Details
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Vaccination with the Epigraph-designed product led to the development of a strong cross-reactive antibody response in mice.
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The Epigraph strategy can be applied to many diverse pathogens. The tool creates a cocktail of vaccine antigens designed to maximize efficacy across a highly diverse population.
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The tool creates a cocktail of vaccine antigens designed to maximize efficacy across a highly diverse population.
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The same basic principles may be applicable to developing a pan-coronavirus vaccine to enable a rapid vaccine response to future coronavirus cross-species jumps.
Algorithm
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An algorithm is a finite sequence of well-defined, computer-implementable instructions, typically to solve a class of problems or to perform a computation.
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It can be expressed within a finite amount of space and time, and in a well-defined formal language for calculating a function.